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/Laura Elizabeth Wright

About Laura Elizabeth Wright

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So far Laura Elizabeth Wright has created 336 blog entries.

Microvascular Injury and Perfusion Changes Induced by Ultrasound and Microbubbles in a Machine-Perfused Pig Liver

Christina P. Keravnou, Ine De Cock, Ine Lentacker, Maria-Louisa Izamis, Michalakis A. Averkiou. Ultrasound in Medicine & Biology, 2016 Nov;42(11):2676-2686. The researchers combined ex vivo machine-perfused pig livers with an image-guided therapy system to investigate applications of ultrasound-driven microbubbles to enhance drug delivery, and demonstrate a versatile, physiologically relevant platform for pre-clinical research.

By | January 4th, 2017|

Detecting default mode networks in utero by integrated 4D fMRI reconstruction and analysis

Sharmishtaa Seshamani, Anna I. Blazejewska, Susan Mckown, Jason Caucutt, Manjiri Dighe, Christopher Gatenby, Colin Studholme Human Brain Mapping, Nov 2016, 37(11), 4158-4178. The researchers describe an fMRI processing and analysis framework for multiecho fetal brain studies where head motion cannot be controlled.

By | December 9th, 2016|

A Stimuli-Responsive, Binary Reagent System for Rapid Isolation of Protein Biomarkers

Barrett J. Nehilla, John J. Hill, Selvi Srinivasan, Yen-Chi Chen, Thomas H. Schulte, Patrick S. Stayton, and James J. Lai. Analytical Chemistry. 2016, 88 (21), 10404–10410. The researchers present a stimuli-responsive binary reagent system, and how it illustrates the potential advantages of nanoscale reagents in molecule and cell isolations for both research and clinical applications.

By | December 21st, 2016|

Mechanical Stress Conditioning and Electrical Stimulation Promote Contractility and Force Maturation of Induced Pluripotent Stem Cell-Derived Human Cardiac Tissue

Jia-Ling Ruan, Nathaniel L. Tulloch, Maria V. Razumova, Mark Saiget, Veronica Muskheli, Lil Pabon, Hans Reinecke, Michael Regnier, Charles E. Murry. Circulation. 2016; 134:1557-1567. The researchers demonstrate how electric pacing and mechanical stimulation promote maturation of the structural, mechanical and force generation properties of human-induced pluriopotent stem cell-derived cardiac tissues.

By | December 21st, 2016|

Virus-Inspired Polymer for Efficient In?Vitro and In?Vivo Gene Delivery

Y. Cheng, R. C. Yumul, S. H. Pun, Angewandte Chemie International Edition. 2016, 55, 12013. Researchers demonstrate a synthetic polymer, VIPER, designed to mimic viral mechanisms of delivery, and that may have potential as a gene delivery platform for cancer therapy and other macromolecule therapeutics.

By | December 21st, 2016|

UW Bioengineering eNews – Fall/Winter 2016

The latest update on UW Bioengineering's advances in research, education, translation and outreach, and the recent achievements of our students and faculty.

By | December 14th, 2016|

Bioengineering Outreach and Honors team adapts toys for children with disabilities at holiday toy hack event

At the TCAT Hack for Access: Holiday Toy Event on Sunday December 11, volunteers from UW and the Seattle community adapted toys for children with disabilities – just in time for the holidays!

By | December 13th, 2016|

Albert Folch featured in “3D Bioprinting Revolution Solidifies Gains” article

Image: A 3D-printed four-valve switch (left) is shown connected to a 3D-printed cell culture chamber (right). [...]

By | December 12th, 2016|

King 5 TV features toy hack event co-hosted by UW Bioengineering Outreach

Image: BioE Ph.D. student Molly Mollica talks with Seattle's King 5 TV about the importance [...]

By | December 12th, 2016|

Ph.D. grad Joshua Buser engineers low-cost diagnostics, mentors next generation

A drive to engineer solutions to global health problems compelled recent Yager lab Ph.D. graduate Joshua Buser to pursue bioengineering. He aims to bring diagnostic testing to low-resource settings – and increase access to affordable health care closer to home.

By | December 9th, 2016|