Lighting up non-fluorescent molecules for biomedical applications
Assistant Professor, Department of Chemistry
University of Washington
February 22, 2018
Foege N130A, Wallace H. Coulter Seminar Room
A major challenge in biology is to understand how individual cells function and respond to perturbations. Optical imaging plays a critical role in overcoming this challenge. We are interested in developing label-free optical imaging tools that are capable of interrogating biological systems noninvasively at single cell or subcellular resolution. In particular, we use stimulated Raman scattering (SRS) microscopy and two-photon absorption (TPA) microscopy to visualize previously invisible molecules and perform precision chemical measurements in living cells and animals. In this talk, I will present our recent efforts in developing SRS and TPA microscopy for biomedical applications.
Dan Fu is an Assistant Professor of Chemistry at the University of Washington. He received his bachelor’s degree from Peking University in China (2003). In 2009, he completed his Ph.D. study at Princeton University under the supervision of Professor Warren Warren, working on the development of novel label-free multiphoton absorption microscopy methods. For postdoctoral training, he worked with Professor Sunney Xie at Harvard University, where he developed hyperspectral stimulated Raman scattering microscopy and applied it to study a wide variety of biological problems. He joined the faculty of the University of Washington in 2015. His main research interests are developing novel optical microscopy for precision chemicals measurements in living biological systems. He is a recent recipient of the Beckman Young Investigator Award..