Research Professor Emeritus
Not accepting graduate students
Donald A. Martyn
- Cardiac Muscle Society
- Biophysical Society
Editorial Responsibilities: Served on numerous occasions (6-8 times per year for the past 8 years) as Reviewer for:
- Biophysical Journal
- American Journal of Physiology
- Journal of Physiology
- Journal of General Physiology
- Journal Muscle Research
- Cell Motility
Post-doctoral Fellow, Center for Bioengineering, University of Washington, 1980-1982
Post-doctoral Fellow Department Physiology/Biophysics, University of Washington, 1978-1980
Ph.D Biology, University of Southern California, 1975
BS Biology, Pacific Lutheran University, 1969
NIH Cardiovascular Post-doctoral Training Grant (1978-1982)
NSF Graduate Training Grant (1969-1975)
Bioengineering Analysis of Physiological Systems 1. Bioengineering 304 (Fall 2005)
Bioengineering Analysis of Physiological Systems 1. Bioengineering 304 (Fall 2004)
Bioengineering Analysis of Physiological Systems I. Bioengineering 304 (Fall, 2003)
Bioengineering Analysis of Physiological Systems II. Bioengineering 305 (Winter, 2002)
Bioengineering Analysis of Physiological Systems I. Bioengineering 304 (Fall, 2002)
Vijay S. Rao, F. Steven Korte, Maria V. Razumova, Erik R. Feest, Hsiao M. Hsu, Thomas Irving, Michael Regnier, Donald A. Martyn. 2013. N-terminal phosphorylation of cardiac troponin-I reduces length dependent calcium sensitivity of contraction in cardiac muscle. J. Physiol. 591: 475-90.
Smith, L., C. Tainter, M. Regnier and D. A. Martyn. 2009. Cooperative crossbridge activation of thin filaments contributes to the Frank-Starling mechanism in cardiac muscle. Biophysical J. 96: 1-11
Gillis, T.E., D.A. Martyn, A.J. Rivera, and M. Regnier. 2007. Investigation of thin filament near-neighbor regulatory unit interactions during force development in skinned cardiac and skeletal muscle. J. Physiol. 580.2: 561-576.
Martyn, D.A., L. Smith, K.L. Kreutziger, S. Xu, L.C. Yu and M. Regnier. 2007. The effects of force inhibition by sodium vanadate on crossbridge binding, force redevelopment kinetics and Ca2+-activation in cardiac muscle. Biophys. J. 92: 1-12.
Moreno-Gonzalez, A, T.E. Gillis, A.J. Rivera, P.B. Chase, D.A. Martyn and M. Regnier. 2007. Thin filament regulation of force redevelopment in rabbit skeletal muscle fibres. J. Physiol. 579: 313-326.
Xu, S., D.A. Martyn and L.C. Yu. 2006. Effects of temperature and ionic strength on myofilament structure of cardiac muscle: disorder-order transformation of the thick filament. Biophys. J. 91: 3768-3775.
Bell, M.G., E.B. Lankford, G.E. Gonye, G.C.R. Ellis-Davies, D.A. Martyn, M. Regnier and R.J. Barsotti. 2005. Kinetics of cardiac thin-filament activation probed by fluorescence polarization of rhodamine labeled troponin C in skinned guinea pig trabeculae. Biophys. J. 90(2): 531-543.
Fuchs, F. and D.A. Martyn. 2005. Invited Review. Length-dependent activation in cardiac muscle: some remaining questions. J. Musc. Res. Cell Motil. 26: 199-212
Warner-Clemmens, E., M. Entezari, D.A. Martyn and M. Regnier. 2005. Different effects of cardiac vs. skeletal muscle regulatory proteins on in vitro measures of actin filament speed and force. J. Physiol. 566.3: 737-746.
Martyn, D.A. 2004. Invited editorial. Myosin-binding protein-C: structural and functional complexity. J. Mol. Cardiol. 37: 813-815.
Adhikari, B.B., M. Regnier, A.J. Rivera, K.L. Kreutziger and D.A. Martyn. 2004. Cardiac length dependence of force and force redevelopment kinetics with altered crossbridge cycling. Biophys. J 87: 1784-1794.
Regnier, M., H. Martin, R.J. Barsotti, D.A. Martyn and E. Clemmens. 2004. Crossbridge vs. thin filament contributions to the level and rate of force development in cardiac muscle. Biophys. J. 87: 1815-1824.
Martyn, D.A., B. Adhikari, M. Regnier, J. Gu, S. Xu and L.C. Yu. 2004. Response of equatorial X-ray reflections and stiffness to altered sarcomere length and myofilament lattice spacing in relaxed skinned cardiac muscle. Biophys. J. 86: 1-10.
Kohler, J., Y. Chen, B. Brenner, A.M. Gordon, T. Kraft, D.A. Martyn, M. Regnier, A.J. Rivera, C.K. Wang and P.B. Chase. 2003. Familial hypertrophic cardiomyopathy mutations in troponin I (K182r, G203S, K206Q) enhance filament sliding. Physiol. Genom. 14: 117-128.
Martyn, D.A., P.B. Chase, M. Regnier and A.M. Gordon. 2002. A simple model of myofilament compliance predicts activation dependent crossbridge kinetics in skinned skeletal fibers. Biophys. J. 83: 3425-3434.
Martyn, D.A. and A.M. Gordon. 2001. Influence of length on force and activation dependent changes in cTnC structure in skinned cardiac and fast skeletal muscle. Biophys. J. 80: 2798-2808.
Martyn, D.A., M. Regnier, D. Xu and A.M. Gordon. 2001. Ca2+ and crossbridge dependent changes in N– and C-terminal structure of troponin C in rat cardiac muscle. Biophys. J. 80: 360-370.
Regnier, M., P.B. Chase and D.A. Martyn. 1999. Contractile properties of rabbit psoas fibres inhibited by berylium fluoride. J. Musc. Res. Cell. Motil. 20: 425-432.
Martyn, D.A., C.J. Freitag and A.M. Gordon. 1999. Ca2+ and crossbridge induced changes in troponin C in skinned skeletal muscle fibers: effects of force inhibition. Biophys. J. 76: 1480-1493.
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