2016 Allan S. Hoffman Lecture

“Drug Delivery Systems: Accelerated Evolution for the Future”

Kinam Park, Ph.D.

Showalter Distinguished Professor of Biomedical Engineering
Weldon School of Biomedical Engineering & College of Pharmacy
Purdue University

4:30 p.m., Monday, October 10, 2016
Genome Sciences Auditorium, Foege South S060
Reception to follow lecture

Abstract

The modern drug delivery technology began in early 1950s. The first 30-year period was highly productive in producing clinically useful formulations for oral and transdermal delivery, while the second half made only limited progresses. Achieving accelerated growth in the future requires understanding the strengths and weaknesses of the current drug delivery approaches. Advance in science and technology, like everything else in life, occurs as a result of repeated trials and errors, and such evolutionary process takes a long time. The question here is whether we can expedite this process to produce clinically useful formulations faster, hopefully in our lifetime. Accelerated evolution can occur only by increasing the number of trials testing diverse ideas, and more importantly, accepting the errors, learning from them, and trying something bold. We the scientists in drug delivery should be persistent in our pursuit of ultimate formulations helping patients. Achieving such goals requires a new, enlightened mindset embracing a paradox and the ability of seeing the invisible gorilla.

Speaker Biography

Professor Kinam Park received his Ph.D. degree in pharmaceutics from University of Wisconsin in 1983. After postdoctoral training at the Department of Chemical Engineering of the same university, he joined the faculty of Purdue University in 1986. He became Showalter Distinguished Professor of Biomedical Engineering in 2006. His research has been focused on utilizing polymers and hydrogels for formulation development of oral and parenteral drug delivery. He also serves as the President of Akina, Inc., specializing in drug delivery technologies and specialty polymers. He is currently the Editor-in-Chief of the Journal of Controlled Release (JCR).

About the Hoffman Lecture

The Hoffman Lecture honors UW Bioengineering’s Dr. Allan Hoffman, now in his 58th year of active research. Dr. Hoffman joined the UW faculty in 1970, when he began to synthesize polymers and hydrogels with special physical and biomedical properties. By combining these special biomaterials with drugs, enzymes and antibodies, he pioneered the applications of temperature and pH-responsive intelligent polymers and hydrogels in the fields of drug delivery, diagnostic assays, and biologically-active and non-fouling polymer surfaces. Much of this research has been carried out in collaboration with Buddy Ratner, Tom Horbett and Patrick Stayton in our BioE Dept. With Dr. Buddy Ratner, Dr. Hoffman is a co-editor of the “Textbook of Biomaterials Science,” now in its third edition. A few of Dr. Hoffman’s awards and recognitions include election as President of the Society for Biomaterials in 1983; receipt of the Founders’ Awards from the Society for Biomaterials (SFB) in 2000 and from the Controlled Release Society (CRS) in 2007. In 2005 he was elected to the National Academy of Engineering (NAE). Dr. Hoffman is one of five members of our department who have been elected to the NAE. In 2016 he received the CRS Foundation Recognition Award for outstanding contributions over his career to drug delivery science and technology. Dr. Hoffman will also receive the 2017 Acta Biomaterialia Gold Medal Award of Acta Materialia at the 2017 SFB meeting in Minneapolis. Dr. Hoffman takes great pride in being an international “ambassador for biomaterials” as he continues very actively to lecture and teach short courses at UW and around the world.

For more information contact Ms. Shirley Nollette (206) 685-2002 or nolletts@uw.edu.