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  • Nancy Allbritton

March 2024 eNews

Nancy Allbritton elected to the National Academy of Engineering [...]

Featured Publications

  • Amino?acid sequence and structural comparison of GA88 and GB88.

A Carboxylate to Amide Substitution That Switches Protein Folds

Valerie Daggett and colleagues performed a comparative molecular dynamics study on the denatured states of two proteins, sharing nearly identical amino?acid sequences (88?%) but different topologies, namely an all?a?helical bundle protein named GA88 and an a+B?protein named GB88.

  • Yeast agglutination

High-throughput characterization of protein–protein interactions by reprogramming yeast mating

The researchers achieved high-throughput, quantitative characterization of protein–protein binding interactions without requiring purified recombinant proteins, by linking interaction strength with yeast mating. Using a next-generation sequencing output, they characterized protein networks consisting of thousands of pairwise interactions in a single tube and have demonstrated the effect of changing the binding environment.

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BioEngage

BioEngage

Connecting UW Bioengineers with Industry
We work closely with Industry Partners to build meaningful, mutually beneficial, and sustainable relationships.

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