UW Bioengineering
Fast Facts
News and Events
The circuitous path: how BioE alumnus Philip Lee found his calling in medicine
UW Bioengineering alumnus Philip Lee: a circuitous journey of discovery and the path to medicine
Events
PharBE alum Robb Poier on the value of lifelong learning
Whether it is serving in the United States Army or working on breakthrough cancer therapies, Robb Poier (PharBE ‘23) has always been passionate about helping people and doing good in the world. more...
Princess Imoukhuede honored with the Professional Impact Award for Diversity, Equity and Inclusion
Princess Imoukhuede, Chair and professor in Bioengineering, received the (AIMBE) Professional Impact Award for Diversity, Equity and Inclusion.
Unveiling therapeutic potential: Exploring the link between Alzheimer’s and Type 2 diabetes
UW Bioengineering Professor Valerie Daggett discussed groundbreaking research on protein aggregation in Type 2 diabetes and Alzheimer's disease.
Featured Publications
Analysis of the Myc-induced pancreatic B cell islet tumor microenvironment using imaging ToF-SIMS.
Lara Gamble and colleagues demonstrate that ToF-SIMS can be utilized to identify large-scale changes that occur in the tumor microenvironment and could thereby increase the understanding of tumor progression and the tumor microenvironment.
Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue
The researchers demonstrate the application of crosslinking mass spectrometry to identify protein structural features and interactions in tissue samples, providing systems structural biology insight into protein complexes as they exist in the mouse heart. The extension of crosslinking mass spectrometry analysis into the realm of tissues opens the door to increasing understanding of protein structures and interactions within the context of the greater biological system.
Loss of PiT-2 results in abnormal bone development and decreased bone mineral density and length in mice
The study's findings suggest that PiT-2 is involved in normal bone development and growth and plays roles in cortical and trabecular bone metabolism feasibly by regulating local phosphate transport and mineralization processes in the bone. Further studies that evaluate bone cell-specific loss of PiT-2 are now warranted and may yield insight into complex mechanisms of bone development and growth, leading to identification of new therapeutic options for patients with bone diseases.
