Microvascular Injury and Perfusion Changes Induced by Ultrasound and Microbubbles in a Machine-Perfused Pig Liver
The researchers combined ex vivo machine-perfused pig livers with an image-guided therapy system to investigate applications of ultrasound-driven microbubbles to enhance drug delivery, and demonstrate a versatile, physiologically relevant platform for pre-clinical research.
Detecting default mode networks in utero by integrated 4D fMRI reconstruction and analysis
The researchers describe an fMRI processing and analysis framework for multiecho fetal brain studies where head motion cannot be controlled.
A Stimuli-Responsive, Binary Reagent System for Rapid Isolation of Protein Biomarkers
The researchers present a stimuli-responsive binary reagent system, and how it illustrates the potential advantages of nanoscale reagents in molecule and cell isolations for both research and clinical applications.
Mechanical Stress Conditioning and Electrical Stimulation Promote Contractility and Force Maturation of Induced Pluripotent Stem Cell-Derived Human Cardiac Tissue
The researchers demonstrate how electric pacing and mechanical stimulation promote maturation of the structural, mechanical and force generation properties of human-induced pluriopotent stem cell-derived cardiac tissues.
Virus-Inspired Polymer for Efficient In?Vitro and In?Vivo Gene Delivery
Researchers demonstrate a synthetic polymer, VIPER, designed to mimic viral mechanisms of delivery, and that may have potential as a gene delivery platform for cancer therapy and other macromolecule therapeutics.