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  • Yeast agglutination

High-throughput characterization of protein–protein interactions by reprogramming yeast mating

The researchers achieved high-throughput, quantitative characterization of protein–protein binding interactions without requiring purified recombinant proteins, by linking interaction strength with yeast mating. Using a next-generation sequencing output, they characterized protein networks consisting of thousands of pairwise interactions in a single tube and have demonstrated the effect of changing the binding environment.

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Connecting UW Bioengineers with Industry
We work closely with Industry Partners to build meaningful, mutually beneficial, and sustainable relationships.

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