Advancing knowledge of vascular calcification for better human health
About the NHLBI Outstanding Investigator Award The National Heart, Lung, and Blood Institute (NHLBI) [...]
About the NHLBI Outstanding Investigator Award The National Heart, Lung, and Blood Institute (NHLBI) [...]
Teamwork, resilience and excellence UW BioE rowers share their musings about rowing and bioengineering [...]
Research Associate Professor Marta Scatena and a team of collaborators show that raising Sphingosine-1-phosphate (S1P) levels in adult mice through conditionally deleting or pharmacologically inhibiting S1P lyase, the sole enzyme responsible for irreversibly degrading S1P, markedly increased bone formation, mass and strength and substantially decreased white adipose tissue.
The Scatena and Giachelli labs developed an animal model that mimicked the structural and functional features of CAVD in people with T2DM, by testing a diabetogenic, procalcific diet and its effect on the incidence and severity of CAVD and AS in the, LDLr-/-ApoB100/100 mouse model.