David and Nancy Auth Endowed Professor in Bioengineering
daggett@uw.edu
Phone: (206) 685-7420
Office: Foege N310B
Valerie Daggett
Dynameomics/bioinformatics
Extremophile proteins
Protein modulators
Protein design
Unfolding diseases
Protein complexes
Single nucleotide polymorphisms
BA, Reed College, 1983
Senior Editor, Protein Engineering, Design and Selection
Editorial Boards: Biochemistry, Current Opinion in Structural Biology, Structure, and elife.
BIOEN 488/588: Computational Protein Design
BIOEN 530: Literary Analysis
Daggett, V. Alpha-sheet: The toxic conformer in amyloid diseases? Acc. Chem. Res., 39, 594-602, 2006.
Rutherford, K. and V. Daggett. Polymorphisms and Disease: Hotspots of Inactivation in Methyltransferases, Trends in Biochem. Sci., 35, 531-538, 2010.
Van der Kamp, M.W., Anderson, P.C., Beck, D.A.C., Benson, N.C., Jonsson, A.L., Merkley, E.D., Schaeffer, R.D., Scouras, A.D., Simms, A., Toofanny, R.D., and V. Daggett. Dynameomics: A comprehensive database of protein dynamics. Structure, 18, 423-435, 2010.
Schaeffer, R.D., Jonsson, A.L., Simms, A.M. and V. Daggett. Generation of a Consensus Protein Domain Dictionary, Bioinformatics, 27, 46-54, 2011.
Towse C.L., Daggett V. When a domain is not a domain, and why it is important to properly filter proteins in databases. BioEssays, 34:1060-1069, 2012.
McCully M.E., Beck D.A.C., Daggett V. Multimolecule test-tube simulations of protein unfolding and aggregation. Proc. Natl. Acad. Sci. USA, 109, 17851-17856 2012.
McCully, M.E., Beck, D.A.C. and V. Daggett. Promiscuous contacts and heightened dynamics increase thermostability in engineered proteins, Prot. Eng. Des. Selec., 26, 34-45, 2013.
In the News
Addressing drug-resistant pathogens by targeting their protective biofilms
2023-07-24T12:11:40-07:00July 24th, 2023|
Valerie Daggett receives the University Faculty Lecture Award
2023-05-23T12:22:18-07:00May 23rd, 2023|
UW News features Valerie Daggett’s groundbreaking Alzheimer’s diagnostic test
2022-12-15T08:49:50-08:00December 6th, 2022|
Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer’s disease, researchers show
2022-08-04T03:42:19-07:00April 16th, 2019|
Valerie Daggett, Wendy Thomas, Rong Tian and Chun Yuan inducted as 2017 AIMBE Fellows
2020-10-26T08:29:23-07:00April 5th, 2017|
Patrick Stayton, Valerie Daggett to present 2016-17 Science in Medicine Lectures
2021-01-21T06:04:29-08:00September 30th, 2016|