Fighting thrombosis by targeting von Willebrand factor
UW Bioengineering researchers identify ways of turning off the function of a blood protein under conditions that may encourage dangerous clots
Monocytes contribute to a pro-healing response in 40 µm diameter uniform-pore, precision-templated scaffolds
Nathan R Chan, Billanna Hwang, Buddy D Ratner, James D BryersJournal of Tissue Engineering and Regenerative Medicine, 2022 March; 16(3):297-310.DOI: 10.1002/term.3280. Epub: 2022 Jan 4.AbstractPorous precision-templated scaffolds (PTS) with uniformly distributed 40 µm spherical pores [...]
Black Dots: High-Yield Traction Force Microscopy Reveals Structural Factors Contributing to Platelet Forces
Kevin M Beussman, Molly Y Mollica, Andrea Leonard, Jeffrey Miles, John Hocter, Zizhen Song, Moritz Stolla, Sangyoon J Han, Ashley Emery, Wendy E Thomas, Nathan J Sniadecki Acta Biomaterialia 2021 Nov 13; S1742-7061(21)00754-6. DOI: https://doi.org/10.1016/j.actbio.2021.11.013 [...]
Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies
Aidan M Fenix, Yuichiro Miyaoka, Alessandro Bertero, Steven M Blue, Matthew J Spindler, Kenneth K B Tan, Juan A Perez-Bermejo, Amanda H Chan, Steven J Mayerl, Trieu D Nguyen, Caitlin R Russell, Paweena P Lizarraga, [...]
Discovery and Characterization of Spike N-Terminal Domain-Binding Aptamers for Rapid SARS-CoV-2 Detection
Nataly Kacherovsky, Lucy F. Yang,Ha V. Dang, Emmeline L. Cheng, Ian I. Cardle, Dr. Alexandra C. Walls, Dr. Matthew McCallum, Prof. Drew L. Sellers, Prof. Frank DiMaio, Prof. Stephen J. Salipante, Dr. Davide Corti, Prof. [...]
Pharmacologic therapy for engraftment arrhythmia induced by transplantation of human cardiomyocytes
Charles Murry, Rong Tian, colleagues find approach suppresses engraftment arrhythmia.