Engrafted Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes Undergo Clonal Expansion In Vivo
Jennifer Davis and colleagues use rainbow reporters to track cells.
Potential role of exosome-based allorecognition pathways involved in lung transplant rejection
Billanna Hwang, James Bryers, Michael S. Mulligan The Journal of Thoracic and Cardiovascular Surgery, Vol. 161, Issue 2, February 2021 | https://doi.org/10.1016/j.jtcvs.2020.04.183 Abstract Innate and adaptive immunity both contribute to allorecognition mechanisms that drive rejection [...]
Fund Black Scientists
Commentary with lead author Kelly Stevens: End funding discrimination.
Microdissected “cuboids” for microfluidic drug testing of intact tissues
Image: A microfluidic platform that permits multiple drug testing of uniformly-sized microscale “cuboids” of live tissue with well-preserved microenvironments. Image by Dr. Albert Folch. Microdissected “cuboids” for microfluidic drug testing of intact tissues Lisa F. [...]
Image-Guided Treatment of Primary Liver Cancer in Mice Leads to Vascular Disruption and Increased Drug Penetration
Sara B. Keller, Dingjie Suo, Yak-Nam Wang, Heidi Kenerson, Raymond S. Yeung and Michalakis A. Averkiou Frontiers in Pharmacology, 30 September 2020 | https://doi.org/10.3389/fphar.2020.584344 Abstract Despite advances in interventional procedures and chemotherapeutic drug development, hepatocellular carcinoma (HCC) [...]
Injectable Biodegradable Chitosan-Alginate 3D Porous Gel Scaffold for mRNA Vaccine Delivery
https://onlinelibrary.wiley.com/doi/full/10.1002/mabi.201800242 Jingxuan Yan, Ruying Chen, Hong Zhang, James D. Bryers. Macromol Biosci. 2019 Feb;19(2):e1800242. doi: 10.1002/mabi.201800242. Abstract: mRNA vaccines have proven to be more stable, effective, and specific than protein/peptide-based vaccines in stimulating both humoral and cellular immune response. However, mRNA's fast [...]