Research in my laboratory focuses on the development of novel methods to answer fundamental questions in biology & medicine. Much of biology & medicine is technology limited in that leaps in knowledge follow closely on the heels of new discoveries and inventions in the physical and engineering sciences; consequently, interdisciplinary groups which bridge these different disciplines are playing increasingly important roles in biomedical research. My lab has developed partnerships with other investigators in the areas of biology, medicine, chemistry, physics, and engineering to design, fabricate, test, and utilize new tools for biomedical and clinical research. Collaborative projects include novel strategies to measure enzyme activity in single cells by capillary and microfluidic electrophoresis, new strategies for software identification of cellular attributes by microscopy, organ-on-a-chip technologies, array-based methods for cell screening, and biodegradable scaffolding for regenerative medicine. An additional focus area is the development of software and instrumentation to support these applications areas. I have >20 issued patents and >25 pending patents which have led to 15 commercial products. Four companies have been formed based on my research discoveries: Protein Simple (acquired by Bio-Techne in 2014 for over $0.3 billion), Intellego, Cell Microsystems (cellmicrosystems.com), and Altis Biosystems (www.altisbiosystems.com). Cell Microsystems currently has world-wide distribution of its unique cell sorting platform through an agreement with the biotechnology company Qiagen and Altis Biosystems has >7 ongoing confidential partnerships with pharma/biotech companies. These accomplishments demonstrate my ability to design and build novel technologies and then translate these technologies into the marketplace to insure their availability to the biomedical research community.