Welcome to UW Bioengineering’s Innovation & Impact!
In this issue, we proudly showcase our latest achievements in bioengineering research, education, leadership and service.
With warm regards and season’s greetings,
Cecilia Giachelli, Ph.D.
W. Hunter and Dorothy Simpson Endowed Chair, Professor
Department of Bioengineering
University of Washington
In our 50 years at UW, we have empowered better health care through biomedical innovation, and transformed lives here in Washington and around the world.
Faculty Research & Awards
This honor recognizes Professor Paul Yager’s prolific spirit of invention, and his work to increase access to health care in developed and developing countries with affordable, point-of-care diagnostic devices.
As a founding member of BioE’s biomaterials research group, Professor Emeritus Thomas Horbett’s work advanced the fields of protein adsorption and surface science.
Assistant Professor Andre Berndt develops biosensors for optogenetics with the goal to advance understanding of neurological diseases, including autism and epilepsy.
Assistant Professor Hao Yuan Kueh aims to develop methods for measuring epigenetic states in single cells using advanced imaging techniques.
Daniel Chiu, joint professor of BioE and Chemistry, seeks to develop radical new technologies for high-resolution mapping of brain tissue, enabling nanoscale analysis of proteins across large regions of the brain.
The Tietze awards support novel stem cell and regenerative medicine research, and enable the advancement of preliminary studies to become competitive for external funding.
Professor Xiaohu Gao’s lab discovered that polydopamine, a material first isolated from shellfish, could dramatically increase the accuracy of ELISA and other common bioassays — by 100 to 1,000 times.
The promotions demonstrate BioE’s excellence in diverse areas of research including disease diagnostics and therapeutics, regenerative medicine and protein engineering.
The October event recognized Professor Emeritus Allan Hoffman’s pioneering contributions to biomaterials research, including the fields of drug delivery, diagnostic assay development and surface science.
Loss of PiT-2 results in abnormal bone development and decreased bone mineral density and length in mice
Shunsuke Yamada et al. (Cecilia Giachelli’s lab)
Biochemical and Biophysical Research Communications
Chemical crosslinking mass spectrometry analysis of protein conformations and supercomplexes in heart tissue
Juan Chavez et al (Rong Tian / James Bruce labs)
Fast and sensitive HPLC–MS/MS method for direct quantification of intracellular deoxyribonucleoside triphosphates from tissue and cells
Sigurast Olafsson et al. (Michael Regnier’s lab)
Journal of Chromatography B
David Younger et al. (David Baker / Eric Klavins labs)
Proceedings of the National Academy of Sciences of the United States of America
Emily Krogstad et al. (Kim Woodrow’s lab)
David Li et al. (Matthew O’Donnell / Lilo Pozzo labs)
Comparison of neovascular lesion area measurements from different swept-source OCT angiographic scan patterns in age-related macular degeneration
Fang Zheng et al. (Ruikang Wang’s lab / University of Miami)
Investigate Opthalmology & Visual Science
A team of UW synthetic biologists led by recent Ph.D. graduate David Younger has reprogrammed yeast’s mating habits to create a sophisticated drug testing platform.
OLA-SIMPLE, an instrument-free, point-of-care device developed by Ph.D. student Nuttada Panpradist and an interdisciplinary team of collaborators, addresses the growing global burden of HIV drug resistance.
The program facilitates the professional development of outstanding postdoctoral researchers as they transition to faculty careers.
With SPLiT-seq, Charles Roco aims to improve the affordability, accessibility and scalability of single-cell RNA sequencing technology.
The interdisciplinary team presented Chromastat, a device that reduces the amount of time and effort needed to maintain cell cultures.
The local, national and international awards recognize BioE student excellence in research, academics and service.
As part of BioE’s academic services team, peer advisors provide prospective undergraduates an inside perspective of the major, and help them navigate opportunities.
Professor Michael Regnier shifted Olympic ambition to a passion for researching and developing therapies for muscular disorders.
BioE students promote accessible play and the importance of inclusive design through toy adaptation — modifying toys to enable their use by children with disabilities.