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  • Noncovalent tagging of siRNA with steroids for transmembrane delivery

Noncovalent tagging of siRNA with steroids for transmembrane delivery

The Gao lab reports on the development of small, bifunctional chemical tags capable of transporting siRNA directly into the cytosol. The bifunctional tags consist of a siRNA-binding moiety that interacts with siRNA non-covalently, and a steroid domain that readily fuses with the mammalian cell membrane.

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BioEngage

Connecting UW Bioengineers with Industry
We work closely with Industry Partners to build meaningful, mutually beneficial, and sustainable relationships.

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