Patterned platforms for tissue engineering
A new approach uses lasers and molecular tethers to pattern 3D cell fate in natural scaffolds for tissue engineering.
Microdissected “cuboids” for microfluidic drug testing of intact tissues
Image: A microfluidic platform that permits multiple drug testing of uniformly-sized microscale “cuboids” of live [...]
Student invention to better diagnose tuberculosis wins NIH prize
A team of UW bioengineering and mechanical engineering undergraduates won second place overall – and took home a $15,000 prize – at the National Institutes of Health’s 9th annual Design by Biomedical Undergraduate Teams (DEBUT) challenge.
Blood vessel twists-and-turns cause cell changes
New 3D model reveals that curvature gives rise to a range of vascular shapes and [...]
Kelly Stevens uses heat to control 3D organ-like tissues
UW Bioengineering's Kelly Stevens Lab and researchers at Rice University created radiatorlike systems to remotely control the positioning and timing of cell functions to build 3-dimensional, artificial, living tissues.
Image-Guided Treatment of Primary Liver Cancer in Mice Leads to Vascular Disruption and Increased Drug Penetration
Sara B. Keller, Dingjie Suo, Yak-Nam Wang, Heidi Kenerson, Raymond S. Yeung and Michalakis A. Averkiou Frontiers [...]
Buddy Ratner wins Bioelastomer Award
Biomaterials expert Buddy Ratner, joint professor in UW Bioengineering and Chemical Engineering, will receive the 2021 Bioelastomer Award
Buddy Ratner, dialysis team win prize for synthetic graft
UW bioengineer Buddy Ratner and his collaborators at Seattle’s Center for Dialysis Innovation (CDI) captured one of six prizes in a national contest to develop new solutions for dialysis care.
UW Bioengineers pivot to develop coronavirus solutions
A number of UW Bioengineering faculty members quickly pivoted and are adapting their research to addressing the needs created by the coronavirus pandemic. From developing rapid at-home tests and protective masks to vaccines and treatments, here is a sampling of some of the ways UW BioE faculty, staff and students are stepping up to help.
How Credible are the COVID-19 Models? Center Aims to Find Out
The multi-institution Center for Reproducible Biomedical Modeling, led by UW Bioengineering Professor Herbert Sauro, is partnering with top U.S. government agencies to determine how credible several commonly used COVID-19 models are.
UW Bioengineers Use Cholesterol Tag to Ease Proteins into Cells
Xiaohu Gao, professor of bioengineering, and his lab have developed a new, cholesterol-based tag system to bring imaging and disease-treating proteins directly into a live cell, bypassing the cell’s defenses. They reported their finding June 19 in Science Advances.
New Weill Neurohub Launches First Projects; UW Bioengineering Faculty Among Project Leaders
Two UW Bioengineering faculty, Amy Orsborn and Azadeh Yazdan-Shahmorad, are project leaders on one of the new Weill Neurohub's five foundational projects announced in March.
Meeting the need for COVID-19 test kits: pivoting from Seattle Flu Study and developing new rapid tests
Barry Lutz, associate professor, and his lab are working on multiple fronts to support the need for coronavirus testing. Within days, his team shifted from helping with the Seattle Flu Study to COVID-19, and his lab began developing community and at-home tests.
Paul Yager developing rapid COVID-19 tests for the home and clinic
The Paul Yager Lab at UW Bioengineering is applying its rapid, low-cost testing technology, called UbiNAAT, to COVID-19 tests, which could be used by untrained people in their homes as well as in health care facilities and low-resource settings around the world.
Patrick Boyle Leads Artificial Intelligence Effort to Predict Risk of Heart Complications from COVID-19
UW Bioengineering Assistant Professor Patrick Boyle and his collaborators in UW cardiology and epidemiology are developing a way to use artificial intelligence to help frontline health care workers predict which COVID-19 patients are at highest risk for heart complications from the illness.
Alyssa Taylor Honored with 2020 UW Distinguished Teaching Award
UW Bioengineering Senior Lecturer Alyssa Taylor has received a 2020 UW Distinguished Teaching Award, which recognizes UW faculty for outstanding dedication and innovations in teaching, mentoring and service to others.
Herbert Sauro, David Baker, Dayong Gao Elected to AIMBE
UW professors and bioengineering faculty Herbert Sauro, David Baker and Dayong Gao have been named fellows of the American Institute for Medical and Biological Engineering (AIMBE).
Students Recognize BioE Faculty with FACET Awards
Three UW Bioengineering core faculty members are being honored by the 2020 Faculty Appreciation for Career Education & Training (FACET) Awards program for positively impacting their students' career and professional development.
With smartphone camera, researchers can create hyperspectral images to analyze skin changes
Modern smartphone cameras can be harnessed to analyze and track skin changes and blood flow dynamics under the skin, report UW Bioengineering Professor Ruikang Wang and his graduate student Qinghua He, in the February issue of Biomedical Optics Express.
NESAC/Bio wins 2020 SFB Technology, Innovation and Development Award; Cole DeForest wins 2020 Young Investigator Award
University of Washington bioengineers have won two awards from the Society for Biomaterials and will receive the honors in May 2020. The NESAC/Bio team of Buddy Ratner, David Castner and Lara Gamble have won the 2020 Technology Innovation and Development Award, and Cole DeForest won the 2020 Young Investigators Award.
Engineered capillaries model traffic in tiny blood vessels
University of Washington bioengineers Ying Zheng and Cole DeForest, working with Seattle Children’s infectious disease researchers, have engineered tiny blood vessels and shed light on how severe malaria infection causes red blood cells to get stuck in the bloodstream’s narrowest passageways. Their paper is published in the Jan. 17 issue of Science Advances.
Bioengineer Nancy Allbritton Named Dean of UW College of Engineering
On Nov. 1, bioengineer Dr. Nancy Allbritton began her role as Frank & Julie Jungers Dean of the College of Engineering at the University of Washington. In addition to her deanship at UW, she holds an appointment in the UW Department of Bioengineering, where she plans to continue her research in single-cell enzymatic assays and organ-on-a-chip technology.
Injectable Biodegradable Chitosan-Alginate 3D Porous Gel Scaffold for mRNA Vaccine Delivery
https://onlinelibrary.wiley.com/doi/full/10.1002/mabi.201800242 Jingxuan Yan, Ruying Chen, Hong Zhang, James D. Bryers. Macromol Biosci. 2019 Feb;19(2):e1800242. doi: 10.1002/mabi.201800242. Abstract: mRNA vaccines have proven to [...]
Biomaterials developer and protein engineer Cole DeForest joins core faculty
UW Bioengineering faculty member Cole DeForest joined the core faculty in January 2019 as joint assistant professor of chemical engineering and bioengineering. He brings expertise in applying synthetic chemistry and materials science to the department’s biomaterials, protein engineering and regenerative medicine research.
Bioengineering Alumnus Wayne Gombotz Receives 2019 UW Diamond Award
UW Bioengineering alumnus Wayne Gombotz (M.S. ’85, Ph.D. ’88) has received the College of Engineering’s 2019 Diamond Award for Distinguished Achievement in Industry. Dr. Gombotz's work has provided the basis of many drug delivery strategies in use and development today; multiple successful therapeutic products and processes to treat cancer, infectious diseases and autoimmune diseases; and it spurred the development of the biotechnology industry in Seattle.
Jay Rubinstein Inducted as 2019 AIMBE Fellow
UW Bioengineering faculty member Jay Rubinstein was inducted to the AIMBE College of Fellows Class of 2019.
Two UW concepts for helping kidney-failure patients advance in national contest
Two ideas put forth by UW's Center for Dialysis Innovation (CDI) - a next-generation wearable dialyzer and a new vascular access graft - advanced to the finals in a national competition aimed at speeding innovations in prevention, diagnosis and treatment of kidney diseases.
3D organ bioprinting gets a breath of fresh air
Bioprinted tissues with entangled vascular networks for air and blood are a major step toward 3D printing of replacement organs. Bioengineers from University of Washington and Rice University teamed to create the 3D bioprinted vascular networks and tested them in mice.
Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer’s disease, researchers show
Researchers led by UW Department of Bioengineering Professor Valerie Daggett have developed synthetic peptides that can target and inhibit the small, toxic protein aggregates that are thought to trigger Alzheimer’s disease. The team reports their achievement in a paper published the week of April 15 in the Proceedings of the National Academy of Sciences.
Humans of UW Bioengineering: Dr. Herbert Sauro
Dr. Herbert Sauro is an associate professor of UW Bioengineering and director of the Center of Reproducible Biomedical Modeling. He also teaches a core course on biological control systems in the undergraduate bioengineering curriculum. Read more to learn about how he took an unusual route to academia by following his passion for combining computational modeling and biology.
Lara Gamble to Lead UW Molecular Analysis Facility
UW Bioengineering Associate Research Professor Lara Gamble has been named director of the UW Molecular Analysis Facility (MAF), a fully-staffed instrumentation facility with extensive microscopy, spectroscopy and surface science capabilities.
Humans Of UW Bioengineering: Dr. Alyssa Taylor
Dr. Alyssa Taylor is a senior lecturer in the UW Department of Bioengineering. Read more to learn how she dealt with the emotional toll of losing her father during graduate school.
Scaffold-Mediated Delivery for Non-Viral MRNA Vaccines
SCAFFOLD-MEDIATED DELIVERY FOR NON-VIRAL MRNA VACCINES https://www.nature.com/articles/s41434-018-0040-9 Ruying Chen, Hong Zhang, Jingxuan Yan, James D. [...]
UW Bioengineering’s James Bryers featured in Science in Seattle
UW Bioengineering Professor James Bryers recently discussed his research with Science in Seattle. His interview [...]
UW Bioengineering welcomes Soraya Bailey as MAB design instructor
Teaching engineering students to create thoughtful, user-focused design, and connecting her students with clinicians and public health experts is Soraya Bailey’s professional passion.
Cardiac systems simulation expert Patrick Boyle joins UW Bioengineering
Computational cardiology expert Patrick Boyle joined UW Bioengineering in September as an Assistant Professor. He will lead the Cardiac Systems Simulation (CardSS) Lab at UW, with the goal to engineer new methods for preventing heart rhythm disorders and sudden cardiac death.
Matthew O’Donnell receives 2019 IEEE Biomedical Engineering Award
Matthew O'Donnell, professor of bioengineering and dean emeritus of the College of Engineering at UW, is recognized “for leadership in biomedical ultrasonics and medical imaging technologies.”
Eric Chudler hosts BrainWorks: Brain-Computer Interface
The latest episode of the Emmy® Award-winning educational program BrainWorks focuses on brain-computer interface (BCI) technology, which offers promising opportunities to treat stroke, spinal cord injuries and other neurodegenerative disorders. BrainWorks is co-produced and hosted by Eric Chudler, research associate professor of bioengineering and the executive director of the Center for Neurotechnology at UW.
Herbert Sauro to lead $6.5M NIH-funded Center for Reproducible Biomedical Modeling
UW Bioengineering Associate Professor Herbert Sauro will lead the $6.5M NIH-funded Center for Reproducible Biomedical Modeling, which aims to develop more predictive models of biological systems for research and medicine.
Deok-Ho Kim receives inaugural IEEE New Innovator in NANOMED award
The New Innovator in NANOMED 2018 award, from the Institute of Electrical and Electronics Engineers (IEEE), recognizes individuals who have demonstrated exceptional early career technical advancement and innovation in the field of nano/molecular medicine and engineering.
Suzie Pun elected to Washington State Academy of Sciences 2018
Suzie Pun, the Robert F. Rushmer Professor of Bioengineering, is one of 14 UW faculty elected to the Washington State Academy of Sciences in 2018. The academy’s mission is “to provide expert scientific and engineering analysis to inform public policymaking in Washington, and to increase the role and visibility of science in the state.”
Stem cells restore working heart muscle in monkeys after heart failure
Monkeys with heart failure regrew working heart muscle after receiving human stem cells, report a UW team led by Charles Murry, professor of bioengineering, pathology and cardiology/medicine.
Targeting sphingosine-1-phosphate lyase as an anabolic therapy for bone loss
Research Associate Professor Marta Scatena and a team of collaborators show that raising Sphingosine-1-phosphate (S1P) levels in adult mice through conditionally deleting or pharmacologically inhibiting S1P lyase, the sole enzyme responsible for irreversibly degrading S1P, markedly increased bone formation, mass and strength and substantially decreased white adipose tissue.
David Castner receives 2018 AVS Medard W. Welch Award
David Castner, UW professor of bioengineering and chemical engineering, is specifically acknowledged for "leading advances in rigorous and state-of-the-art surface analysis methods applied to organic and biological samples."
Master’s student Dylan Guelig developing rapid flu, Ebola tests with focus on global health
UW Bioengineering master's student Dylan Guelig is developing a cartridge-style two-dimensional paper network test that can detect minute amounts of proteins present in deadly flu viruses as well as a similar test for the Ebola virus.
Gerald Pollack to join Nobel Laureates to present seminar before UK’s House of Lords
Professor Gerald Pollack will share the podium with Nobel Laureates Luc Montagnier (Medicine) and Brian Josephson (Physics) in a special seminar on “New Horizons in Water Science" to be held at the Royal Society of Medicine in London in July 2018.
BioE startup NanoSurface Biomedical wins 2018 Seattle Angel Conference
NanoSurface Biomedical, a startup co-founded by UW BioE alumnus Elliot Fisher (’16) and his former research advisor Deok-Ho Kim, associate professor of bioengineering, won $125,000 of funding in the final round of the Seattle Angel Conference on May 16.
Suzie Pun named 2018 Marsha L. Landolt Distinguished Graduate Mentor
Suzie Pun, the Robert F. Rushmer Professor of Bioengineering, has been named the 2018 recipient of the Marsha L. Landolt Distinguished Mentor Award, in recognition of her outstanding mentoring of graduate students.
Deok-Ho Kim and team awarded Human Frontier Science Program Research Grant
The international research team will investigate the dynamics of collective cell migration on curved surfaces. They aim to understand the mechanistic details of organism development and tissue repair, which could inform approaches in tissue engineering and regenerative medicine.
James Bryers presents at UW Medicine/Allen Institute/Fred Hutch SLU Collaborative
James Bryers, UW professor of bioengineering, presented at March 29's South Lake Union (SLU) Collaborative [...]