Potential role of exosome-based allorecognition pathways involved in lung transplant rejection
Billanna Hwang, James Bryers, Michael S. Mulligan The Journal of Thoracic and Cardiovascular Surgery, Vol. [...]
Fund Black Scientists
Commentary with lead author Kelly Stevens: End funding discrimination.
Microdissected “cuboids” for microfluidic drug testing of intact tissues
Image: A microfluidic platform that permits multiple drug testing of uniformly-sized microscale “cuboids” of live [...]
Image-Guided Treatment of Primary Liver Cancer in Mice Leads to Vascular Disruption and Increased Drug Penetration
Sara B. Keller, Dingjie Suo, Yak-Nam Wang, Heidi Kenerson, Raymond S. Yeung and Michalakis A. Averkiou Frontiers [...]
Injectable Biodegradable Chitosan-Alginate 3D Porous Gel Scaffold for mRNA Vaccine Delivery
https://onlinelibrary.wiley.com/doi/full/10.1002/mabi.201800242 Jingxuan Yan, Ruying Chen, Hong Zhang, James D. Bryers. Macromol Biosci. 2019 Feb;19(2):e1800242. doi: 10.1002/mabi.201800242. Abstract: mRNA vaccines have proven to [...]
Patterned human microvascular grafts enable rapid vascularization and increase perfusion in infarcted rat hearts
Ying Zheng and colleagues demonstrate that engineered perfusable microvessel grafts enhance vascular remodeling and accelerate coronary perfusion, potentially supporting cardiac tissues after implantation.
Scaffold-Mediated Delivery for Non-Viral MRNA Vaccines
SCAFFOLD-MEDIATED DELIVERY FOR NON-VIRAL MRNA VACCINES https://www.nature.com/articles/s41434-018-0040-9 Ruying Chen, Hong Zhang, Jingxuan Yan, James D. [...]
Core-shell nanoparticles for targeted and combination antiretroviral activity in gut-homing T cells
Kim Woodrow and colleagues demonstrate a LCNP that has the potential to co-deliver ARVs and mAbs for eradicating HIV reservoirs.
Use of En Face Swept-Source Optical Coherence Tomography Angiography in Identifying Choroidal Flow Voids in 3 Patients With Birdshot Chorioretinopathy
Ruikang Wang and colleagues demonstrate that swept-source OCTA may represent a new and noninvasive method for detecting and monitoring disease activity in BSCR.
Human embryonic stem cell–derived cardiomyocytes restore function in infarcted hearts of non-human primates
Charles Murry and colleagues demonstrate that remuscularization of the infarcted macaque heart with human myocardium provides durable improvement in left ventricular function.